TTS is classified into 2 levels by the CDC.
AstraZeneca, a British pharmaceutical giant, has admitted that its Covid-19 vaccine may cause a rare side effect known as thrombosis with thrombocytopenia syndrome (TTS). This recognition follows a lawsuit filed against the company, alleging serious harm and deaths linked to the vaccine.
According to court documents, Covishield, a vaccine developed by AstraZeneca and the University of Oxford and manufactured by the Serum Institute of India, can, in rare cases, lead to this condition. This vaccine has been widely administered across India during the Covid-19 pandemic.
What is thrombosis with thrombocytopenia syndrome (TTS)?
Thrombosis syndrome with thrombocytopenia (TTS) is a rare disease in which blood clots form in unusual places in the body and the number of platelets in the blood decreases. Platelets are small cells that help blood clot. Having too little can therefore be dangerous.
The disease has been seen in people who received adenoviral vector COVID-19 vaccines, such as Vaxzevria, Covishield (AstraZeneca), and the Johnson & Johnson/Janssen COVID-19 vaccine. TTS appears to occur because the immune system responds to the vaccine by producing antibodies that attack a protein involved in blood clotting.
TTS is classified into 2 levels by the CDC.
Level 1
- Rare blood clots, such as in the brain or intestine, sometimes alongside more typical blood clots in the legs or lungs.
- Low platelet count (less than 150,000 per microliter).
- Positive anti-PF4 ELISA tests can help confirm the diagnosis but are not always necessary.
- Level 1 cases are generally more serious and riskier.
- This is more common among young people.
Level 2
- Common blood clots, such as in the legs or lungs.
- Low platelet count (less than 150,000 per microliter).
- A positive anti-PF4 ELISA test is necessary for diagnosis.
TTS: Symptoms
Symptoms of TTTS may include severe headaches, stomach pain, leg swelling, difficulty breathing, and problems thinking or seizures. If a person experiences these signs after receiving a vaccine, they should seek medical attention immediately.
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